MOONSHOT RESEARCH & DEVELOPMENT PROGRAM, Moonshot Goal 2: Realization of ultra-early disease prediction and intervention by 2050, Project Manager (PM): Hideki KATAGIRI (Professor, Tohoku University Graduate School of Medicine)

Challenge for Eradication of Diabetes and Comorbidities through Understanding and Manipulating Homeostatic Systems

Project Manager
Hideki Katagiri
Professor, Tohoku University
Graduate School of Medicine

In this moonshot project, we aim to realize a society, by 2050, in which diabetes and its complications can be easily detected at a very early stage, allowing reversal of these disease conditions. To achieve this goal, we are actively collaborating with researchers in various fields, encompassing not only many areas of medical science but also pharmacology, information science, engineering, and mathematics. We are conducting research to elucidate the mechanisms that maintain homeostasis at the whole-body level, focusing on inter-organ communication, to define the very early stages of diabetes and its complications, to develop simple detection methods, and to devise optimally effective remedial strategies.

News & Topics

2022.11.21
Achievements for FY2022 have been updated.
2022.9.21
[Press Release] Nakamura Group's research results "Researchers discovered brain neural pathway for the "love hormone" oxytocin to burn fat" has been released. For press release, click here. For the paper, click here.
2022.9.8
Kimura Group's review "Short-chain fatty acid receptors and gut microbiota as therapeutic targets in metabolic, immune, and neurological diseases" has been published online in Pharmacol Ther.
2022.8.19
Yoshimoto Group's original paper "Simultaneous measurement of central amygdala neuronal activity and sympathetic nerve activity during daily activities in rats" has been published online in Exp Physiol.
2022.4.28
Achievements for FY2021 have been updated.
2022.4.28
Project Manager Katagiri's review article was published in Int Immunol.
2022.4.1
Dr. Rikuhiro Yamada of RIKEN has joined the project as a new principal investigator.
2022.3.31
Kimura Group's original paper "Dietary medium-chain triglyceride decanoate affects glucose homeostasis through GPR84-mediated GLP-1 secretion in mice" has been published online in Front Nutr.
2022.3.29
Dr. Yuka Fujiki's (Chiba Group) original paper "A general model of hierarchical fractal scale-free networks" has been published online in PLoS One.
2022.3.26
Moonshot Goal 2 Public Symposium 2022 "From Cure to Prevention" was held.
2021.11.26
Nakamura Group's review "Central sympathetic network for thermoregulatory responses to psychological stress" has been published online in Auton Neurosci.
2021.11.25
Website is now open!
2021.3.20
Moonshot Goal 2 Kick-off Symposium was held.

MOONSHOT RESEARCH & DEVELOPMENT PROGRAM
Challenge for Eradication of Diabetes and Comorbidities through Understanding and Manipulating Homeostatic Systems
Project Manager (PM): Hideki KATAGIRI (Professor, Tohoku University Graduate School of Medicine)
For inquiries about the project, please contact: moonshot-katagiri@proj.med.tohoku.ac.jp

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